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United States

Internship

Remote

$47/hr - $52/hr

Intern

Roche is hiring a 2027 Summer Intern in Computational Science to develop and benchmark bioinformatics algorithms for sequencing data. The intern will build software and present results to stakeholders, supporting secondary analysis for genomic sequencing applications.

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Responsibilities

Algorithm Development
Benchmarking
Software development
Presenting results to stakeholders

Qualification

Required

Must be pursuing a PhD (enrolled student)
Bioinformatics, Computer Science, Computational Biology
Advanced experience developing bioinformatics algorithms for secondary analysis of sequencing data
Demonstrated expertise in detecting genetic variation in challenging genomic contexts, including repeat regions, paralogs, pseudogenes, and highly homologous loci
Strong understanding of haplotype phasing, read alignment, local or de novo assembly, scaffolding, and pangenome methods
Experience developing tools for one or more of the following:Repeat expansion or repeat-genotype analysis, Paralog- or pseudogene-aware variant calling, Long-read or highly accurate sequencing analysis, Haplotype reconstruction and phasing, De novo or targeted assembly, Graph genomes or pangenome analysis
Strong programming skills in Python and/or C++, with experience building reproducible, tested software
Experience evaluating algorithms with representative datasets and quantitative performance metrics
Currently enrolled in or recently graduated from a degree program in bioinformatics, computational biology, computer science, statistics, mathematics, genomics, or a related field

Preferred

Demonstrated record of publications, preprints, or equivalent technical contributions describing novel algorithms or methods for variant detection and genotyping
Research experience focused on difficult-to-map regions of the genome, including repeats, paralogs, pseudogenes, segmental duplications, and other highly homologous loci
Publications or documented contributions involving one or more of the following:Repeat-variant detection or genotyping, Haplotype phasing and reconstructionLocal, targeted, or de novo assembly, Scaffolding and contig generation, Pangenome or graph-based analysisLong-read sequencing analysis, Paralog- or pseudogene-aware variant calling
Ability to explain algorithmic innovations, validation methodology, limitations, and performance results clearly
Evidence of translating research methods into reproducible prototypes or usable bioinformatics tools

Benefits

This internship position is fully remote.
A stipend, based on location, will be provided to help alleviate costs associated with the internship.
Paid holiday time off benefits

Roche is a pharmaceutical and diagnostics company that offers medicines and diagnostic tests for various medical conditions and diseases.

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